>>19505458I don't know about the PFS that stays for decades after you took it for a week, those guys probably have something else going on. But I did get sides after taking it for 6 months and ignoring them, and it took 6 months after a quit to go back to normal. Fin binds with 5ar but your body completely replaces all of it after a while. Other than downregulating your receptors, I don't think it can permanently shut off production.
Also, DHT is important downstream for several neurotransmitter hormones like GABA and allopregnalone, which might not affect everyone the same but if you're already prone to low mood or a light sleeper it's going to be noticeably worse.
It's probably worth it if you're in your 20s because your body will just tank the hit but DHT gets more important for well being, keeping weight off and feeling like a man when you get past 30. I'm not trying to convince anyone not to take it by the way so don't mald at me, all of the above is well established.