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In 2019, Trump and Pence are both assassinated simultaneously in a premeditated attack.
In 2020, the next election occurs. Ivana Marie Trump wins with little effort. The election of another 'Trump', no matter how different, is enough to throw countries we already had shaky relations with into turmoil. North Korea finally snaps and threatens Japan, to little avail as they act as if the threat is an empty one. They soon discover it is not.
America then declares war on Korea when Akihabara is bombed, China steps in to back them up, and MAD nearly occurs.
Several important American cities were bombed, and the new temporary capitol is currently in Kentucky at Fort Knox. We've since then begun rebuilding, and had quite a few years to do so... But we were still recovering when CERN stepped in. Progress grinded to a halt without the infrastructure this world practically lived by: The Internet.