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Yes.
The Orientation Model of Human Sexuality is a social program, a modern cultural invention. There are no supernatural attributes you are "born with", ecologists throughout the 1990s popularized anthropomorphized models of human sexuality. For a decade they convinced people that giraffes were gay, it turns out they were just doing social dominance completely unrelated to reproduction.
As an adult animal, lack of interest in the opposite sex, or prolonged interest in the same sex, is a form of reproductive dysfunction and arrested development. Socio-sexual interactions are the highest and most cognitive form of physiological interaction and are meant to clock in around adolescence. Child abuse, emotional and physical, even neglect can cause developmental difficulties in the final stages of animal functioning.
In the 1980s and 1990s, psychologists at the APA decided that homosexuality was not a form of reproductive and psychological dysfunction in the adult animal, because all of the difficulties experienced by people with these disorders were due to "externalities" and "stigma". That's right, there's actually nothing wrong with having no interest in reproduction. If 80% of baboons became "gay" (permanent, lifelong, exclusive attribute from birth), it would be regarded as catastrophic failure of their animal functioning and an imminent extinction. So we know there are intrinsic, deleterious effects when reproduction doesn't work correctly.
Of course, impaired psycho-social functioning has other effects that aren't related to reproduction, and damage the overall quality of life of people who have those disorders. Instead of trying to use what we know about organismal biology to TREAT these people (sexual behaviors are extremely sensitive to conditoning, see fetishes), we have decided that it is unethical. Similarly, see transgenderism (feminity is an expensive consumer product and female animals don't really exist).