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To treat the problem, the doctors - from the Lebanese University in Lebanon - used laser therapy to break up the mass. Ultrasound shockwaves were emitted from the device to the patient's abdomen, on the outside of the body.
Once broken into pieces, the stones were removed using forceps during a three-hour procedure.
Because the stone was so large, it was pressing against the woman's bladder, which reduced its capacity and led to further leakage of urine.
A far more common type of crystalized stone is a kidney stone: which form in a similar way to vagina stones.
Hard clumps of minerals stick together in concentrated urine, forming a stone.
Around 11 percent of men and six percent of women suffer them in their lifetime.
The woman had spastic cerebral palsy, which leads to muscle stiffness mostly in the legs, with the arms less affected or not at all affected.
Scientists used to think that the disorder was caused by a lack of oxygen during the birth process, but now they think this is only true for a small number of cases.
Roughly one million people have cerebral palsy in America, and about 10,000 babies are born with it every year.
The researchers said cerebral palsy patients who often lie down for long periods and have urinary incontinence are at risk of developing vagina stones.
