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Have you ever thought you were in love with someone but then realized you were just staring in a mirror for 20 minutes?
As (post-)humanity emerges from the neurochemical Dark Ages, enriched dopaminergic function in particular may sharpen the sheer intensity and meaningfulness of every moment of conscious existence. For a generation whose lifetimes span both modes of awareness, it will be as if they had just woken up. They will feel they had hitherto been sleep-walking through life in a twilit stupor. Thereafter their former mundane and minimal existence may be recalled only as some kind of zombified trance-state whose nature they were physiologically incapable of recognising.
The Main Library at Indiana University sinks over an inch every year because when it was built, engineers failed to take into account the weight of all the books that would occupy the building.