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The basic anime apocalypse trope;
Invasion of interdimensional beasts and abomination, 2/3 of humanity goes extinct.
Remaining humans shelter themselves and with the best and most crazy scientists and experts still alive, an artificial super species gets created, part human(+ animalistic features), part machine and rumors say even those creatures out there are part of their genetic sequence so they can use for the layman's eye looking magical abilities, which are for everyone of them unique, also they are all lolis, but no will ever question this fact, okay.
So basically just magical cyborg girl ripping and tearing Lovecraftian aliens with lots of explosions and shit, maybe some gore and tentacle parasite rape included.
