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1833 Dr. William Beaumont, an army surgeon physician, pioneers gastric medicine with his study of a patient with a permanently open gunshot wound to the abdomen and writes a human medical experimentation code that asserts the importance of experimental treatments, but also lists requirements stipulating that human subjects must give voluntary, informed consent and be able to end the experiment when they want. Beaumont’s Code lists verbal, rather than just written, consent as permissible (Berdon).
1845 – 1849 J. Marion Sims, later hailed as the “father of gynecology,” performs medical experiments on enslaved African women without anesthesia. These women would usually die of infection soon after surgery. Based on his belief that the movement of newborns’ skull bones during protracted births causes trismus, he also uses a shoemaker’s awl, a pointed tool shoemakers use to make holes in leather, to practice moving the skull bones of babies born to enslaved mothers (Brinker).
1895 New York pediatrician Henry Heiman infects a 4-year-old boy whom he calls “an idiot with chronic epilepsy” with gonorrhea as part of a medical experiment (“Human Experimentation: Before the Nazi Era and After”).
1896 Dr. Arthur Wentworth turns 29 children at Boston’s Children’s Hospital into human guinea pigs when he performs spinal taps on them, just to test whether the procedure is harmful (Sharav).
1900 A U.S. doctor doing research in the Philippines infected of number of prisoners with the Plague. He continued his research by inducing Beriberi in another 29 prisoners. The experiments resulted in two known fatalities. GERM WARFARE The Hall of Shame
1911 Turkey established gun control. From 1915-1917, 1.5 million Armenians, unable to defend themselves, were rounded up and exterminated.
1915: A doctor in Mississippi produced Pellagra in twelve white Mississippi inmates in an attempt to discover a cure for the disease. GERM WARFARE The Hall of Shame