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Here is my anecdotal evidence:
I've been smoking on and off since high school up until four years ago when I started smoking every day. I have disabling migraines about 4 times a month which started when i was 12. smoking regularly has completely removed my migraines for the past four years. When I mean smoking, it can be flower, hash, wax, resin, whatever, as long as it is high quality. Doctors have never found anything wrong with me and always want to try experimental drugs which I deny. Tolerance hasn't been a big issue but I did take a two week break for a new job.