>>3030318>>3030309>>dementia>>alzheimers>>Genetic muscle diseasesConclusion
In conclusion, efforts to explore the benefits of lifestyle or pharmacological interventions in improving native β-cell function are necessary and should be timely. A very recent meta-analysis involving almost 19 000 patients revealed no long-term benefit to exogenous insulin therapy in type 2 diabetics, but rather found only potential harm,47 highlighting the need to focus on mechanisms that improve endogenous glucose control. Altogether, our findings suggest that βHB may be involved in improved β-cell outcomes in states of increased ketogenesis and provide a focus for future therapies to enhance β-cell maintenance in type 2 diabetes.
FIGURE 3: β-Hydroxybutyrate favourably alters mitochondrial function.
https://insulinresistance.org/index.php/jir/article/view/25/58 