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>UsingclomiPRAMINEtogether withmirtazapinecan increase the risk of a rare but serious condition called theserotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate,fever,excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp,nausea,vomiting, anddiarrhea. Severe cases may result in coma and even death.