>>17185843often times, due to drug prohibition loopholes, these designer drugs will be sought after due to their legality. new designer drugs pop up every so often without being tested for safety or even effects because the other designer drugs just get criminalized. they often don't have regulations in their chemical processing, so dangerous chemicals could be left as residue. people are basically human guinea pigs when taking these substances, and because prohibition takes away any sort of safe source/sort of recreational substances, substance abusers are left with little choice but to rely on this market. there are communities online that discuss harm reduction in regards to some of these substances. some even prefer the alternatives, like how methoxetamine, an analogue of ketamine, is the holy grail of research chemicals because it's exclusivity came from being made illegal a while ago. the psychonaut wiki and erowid are good places to find the subjective effects of a substance, but the story of substance abuse is not one that words capture.