>>19892984>You can google this all day and you will never find an actual proven cause of arterial inflammationexcept you can and I've literally published multiple papers on this
systemic inflammation is always a negative but localized inflammation is the reason specifically for coronary artery disease; it's the entire reason why you very rarely see "radial artery disease" or "internal mammary artery disease"
it's a combination of
>high pressure>high velocity>high shear stressthat stresses the endothelial barrier
The main sites of CAD are:
>LAD-LCX bifurcation>LAD-1st Diag bifurcation>RCA ostium to RIMA (right inferior marginal)Why? High velocity and high pressure causing high shear stress because the sinotubular junction has the highest velocity and pressure of blood anywhere in the body, which is right where the coronaries take off from.
The main sites of peripheral artery disease are:
>carotid sinus bifurcation of internal and external carotid>femoropopliteal junction>BTK peroneal and ATA arteries where significant necking-down happensWhy?
same exact reason, high differential pressure and velocity relative to other parts of the circulatory system.
if you are predisposed to heart disease the ONLY thing that you can reasonably do is eat an antioxidant diet and manage your blood sugar, plus heavy resistance training and some cardio
specifically resistance training is important because the valsalva maneuver and regular wide fluctuations in thoracic pressure will actually keep your vessels mobile and encourage vascular remodeling to manage any plaque that's currently present.
sugar is shit, but not for the reason you think that it is. almost no sugar that you'll get in the US other than table sugar is actual glucose and sucrose. Most of it is HFCS which is godawful for you. Artificial sweeteners like sucralose and aspartame are even worse, so continuing to drink "zero sugar" sodie-pops on a "low sugar diet" is actually worse for you
