>>20850009Constance "Connie" Tucker, better known as "Meemaw" is the mother of Mary Cooper and the maternal grandmother of Sheldon Cooper, George Cooper Jr. and Missy Cooper, as well as the great-grandmother of Missy Cooper's son, Constance Cooper and Leonard Cooper. She is Sheldon's favorite of all his living family members, as he shows her no resentment at all, unlike his resentment toward his other family members, except his mother. She was widowed in 1985 when her husband, Sheldon's grandfather "Pop-Pop", passed away. She had only been mentioned and had not appeared in the series, until "The Meemaw Materialization" during which she made her first appearance, in February 2016. She is played by Academy Award nominee June Squibb. In Young Sheldon, she is portrayed by actress Annie Potts.
Like Sheldon has explained, Meemaw is a wonderful, warm, loving, sweet and wise grandmother who's protective and caring for Sheldon. She calls him "Moon-pie" because he's so "nummy-nummy, she could just eat him