>>3741584 Eating whole fruit, it is almost impossible to consume enough fructose to cause harm.
Fruits are loaded with fiber, water and have significant chewing resistance.
For this reason, most fruits (like apples) take a while to eat and digest, meaning that the fructose hits the liver slowly.
Plus, fruit is incredibly fulfilling. Most people will feel satisfied after one large apple, which contains 23 grams of sugar, 13 of which are fructose (4).
Compare that to a 16oz bottle of Coke... which contains 52 grams of sugar, 30 of which are fructose (5).
A single apple would make you feel quite full, automatically making you eat less of other foods. However, a bottle of soda has remarkably poor effects on satiety and people don't compensate for the sugar in sodas by eating less of other foods (6).
When fructose hits your liver fast and in large amounts (soda and a candy bar) then that can have disastrous consequences... but when it hits your liver slowly and in small amounts (an apple) then your body can easily take care of the fructose.
Also, let's not forget the evolutionary argument... humans and pre-humans have been eating fruit for millions of years. The human body is well adapted to the small amounts of fructose found in nature.
Whereas large amounts of added sugar are harmful to most people, the same can NOT be said for fruit. Period.
