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Research has indicated that ghost sightings may be related to degenerative brain diseases such as Alzheimer's disease.[10] Historically, certain toxic and psychoactive plants (such as datura and hyoscyamus niger), whose use has long been associated with necromancy and the underworld; have been shown to contain anticholinergic compounds that are pharmacologically linked to dementia (specifically DLB) as well as histological patterns of neurodegeneration.[11][12] Older reports linked carbon monoxide poisoning to ghost-like hallucinations.[1
