>>2930661In short they have a wider color range. Mostly this gets memed for making pure black/white background, but it applies in general. They require CFG rescale (of any kind) otherwise it fries the contrast. In regards to loras, regular ones still work but are a bit weaker. v-pred specific loras do not work with regular (eps-pred) models at all.
>>2930665You don't need comfy, old A11 and new Forge can use it too. If you do not activate v-pred it will generate pure noise, the checkpoint cannot "work without".