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To put it shortly:
It is a game. A game that is great but like other games, it is at the whim of the creator how the universe runs. Samus is a kick ass individual who is still very human. *unlike some other super soldier that has little to no emotion nor is human..possibly *cough halo*
All in all, anything can happen in the metroid universe if the creator wills it. So whether or not she is sterile, wants a kid, has a sister, or what ever the case..its all up to yoshio Sakamoto. NOW! On with the samus ecchi!
Besides, look at Dragon ball Z..Try to Logically explain that thing with out being confused timeline wise or anything for that matter. Movies and all..