>>2800800How are you upscaling and what upscaler are you using? I use R-ESRGAN4x+ Anime6B and I'm sure other anons have their favorites.
Also if you're just upscaling using the built-in upscaler in the extras tab, that's gonna be sub-par. Try something like Tiled Diffusion (a.k.a. Multidiffusion) or SD Ultimate Upscale. I cover upscaling using Tiled Diffusion in the noob guide linked in the FAQ.