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I just cleaned my chain with a cheap chain cleaning tool, with the brushes inside, I got off ebay and some mean green degreaser. I wiped it off with a rag and let it sit for a couple hours before using pic related on it. Worked fine.
It might just be in my head, but it feels like using the easiest gear going up hills takes a little more effort? Other than that everything is quieter and seems to work fine.