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I am switching to a Shimango system, powermeter shimano crankset, shimano cassette, and everything else Campy.
Shimano and campy Cassettes are fully compatible/interchangeable, as I found out today. However the Campy chainline is 44.5, and Shimano is 43.5.
Since the cassettes are compatible, therefore the chainline difference is merely an issue of the crankset clearing the frame. Does this make sense?