>>1264231Not really.
The A380 has a lengthy start-up checklist, but I will admit that the checklist is on the ECAM, and that it will self-check.
I know that the A380 has a lot of interesting features (like auto-pilot automatically following TCAS resolution advisories and Brake to Vacate which brakes the aircraft perfectly to the right speed for the taxiway while on auto-landing), but the A380 becomes a very complex machine once systems are not being used, like in any Airbus model.
There's a big difference between normal manual flight and high automation flight, at least in terms of inputs.
Any Airbus is specifically designed to be easy to learn how to use. It's what reduces pilot errors and also makes it simpler for pilots to understand what exactly each part of the aircraft does.
Meanwhile, Boeing puts an MCAS in their planes, doesn't tell pilots that it exists and also doesn't tell them what activates it and what it does and why until a plane crashes.
The most complicated aircraft to operate aren't technically aircraft, they're spacecraft. The Space Shuttle, the Apollo craft, the Soyuz, the Mercury, the Gemini. They all require a large amount of system knowledge and understanding of how the craft operate and what does what, especially since spacecraft also need to operate in the vacuum of space, all while often sitting on several tons of explosives.
I'd say that the Space Shuttle was the most complex to operate. Flew like a brick in atmosphere, had huge black zones during launch and was not a simple craft to navigate in orbit.