>>1403761>>1402429>>1404089Boeing was right to kill 757. Nobody was buying 757 because it's larger plane than A321 with much higher MTOW, but the cargo hold isn't designed to accept ULD containers. The only way to be competitive against A321 since B757 has worse fuel economy on per passenger seat basis is to take advantage of higher MTOW and carry heavy air cargo, but since you can't put in ULD, you have to have loaders crawl into the hold and secure the heavy cargos with ropes. So, airlines have to incur higher labor cost and longer turn around time between flights to take advantage of one thing B757 does better than A321.
Boring would have to significantly change the fuselage of B757 significantly to make it accept ULD to compete with A321, but if you change the external dimensions of a fuselage, it's a brand new plane as far as FAA is concerned, and 757 pilots have to receive lengthy re-training to fly the hypothetical ULD container-accepting B757 refresh.
That's why Boeing killed 757, and it was the right decision.