>>1333128>>1333203>>1333619>>1333804>>1333944>you cannot vaccinate against borelia burgdorferi IN HUMANS because the toxin fighting antibodies leave your body too quickly to be effectivewow better tell Valneva before they move into Phase 2 trials this year!
also WHAT fucking toxin? B. burgdorferi pathogenicity is mediated by surface proteins.
>Outer surface protein A (OspA) has been the basis for at least two different vaccines targeting LB; LYMErix (SmithKline Beecham) and ImuLyme (PasteurMérieux-Connaught). >Both vaccines contained only OspA from B. burgdorferi as antigen, but only LYMErix was licensed and available for customers from 1998–2002, when it was voluntarily withdrawn from the market (thanks to the vaccine scare)>If you know anything about the human immune system you know that antibodies do not bind to bacteria because they have no protein coat(and therefore no antigen for antibodies to connect with), so your body cannot create an “immunity” to a bacterial infectionB. burgdorferi literally has outer membrane proteins. and even if it didn't, every statement you've made so far would still be wrong.
>doesn't know that macrophages, B cells and dendritic cells can detect bacterial capsule structures and promote immunity>doesn't know about T cell independent responses>doesn't know the absolute BASIC fact that antibodies can bind to more than just proteins, like fucking BACTERIAL POLYSACCHARIDES>thinks toxoids are the only type of vaccine we've developed so faryour ability to be supremely confident in broadcasting your complete ignorance is astounding, almost pre-medfag like. you can stop blowing dated misinformation out of your ass now.
