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With all due respect: why do you focus on nuclear/radiological dangers so much?
The closest Nuclear Power Plant is located 340m from me, another 580km. I can see you know nuclear survival well, many people skip on it for being really hard to memorize. There are many life disruptions I'm trying to prepare for that are much more likely. Injury or health problems (remember I have two kids), financial problems including job loss or incoming financial crysis, house fire, building being damaged due to extreme weather (we had 30 years old trees uprooted last year from the lawn in front of our balcony), blackouts (actually as we speak Poland is borrowing power from neighbouring countries), supply chain shortages, finally widespread disaster or war forcing us to evacuate.
I'm not planning to live on the streets with two toddlers, becoming refugees in another country or moving to small town (I have family in both) seems much better at the moment
I do have basic respirators in my pack for the whole family. If fitted properly they would filter out most dust (radioactive or not) and even viruses to a degree
As for the garden/hunter's cart. Have you tried to move cross country with it? If not are you sure it would work as you imagined? Hobos might have a reason, but why aren't carts used widely by hikers?
What I did was practiced the same route with stroller and on foot multiple times WITH LIVE KIDS and came to a conclusion car/baby carriers are a way to go for us