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I've got an REI Flashback 18 (pictured) for my EDC stuff (jacket, lunch, book, camera, etc)
I've got an REI Flash 22 for day hikes.
I've got a North Face Crevasse for camera gear and/or over night to weekend travel.
I've got a mkII REI Lookout 40 for extended hiking, day summits, camping, overnight backpacking or snow shoeing. (The latest mkIII Lookout 40 has been a complete flop, btw, it'll be going on clearance soon)
I've got an Osprey Porter 46 for extended travel.
I actually don't have an extended use pack right now, but I'm probably going to pro-deal a Gregory Savant 58 after the holiday pay comes in.
>Build
6ft, 200lbs with a 23 inch shoulder span (this makes fitting tricky sometimes)
>regrets
None, every pack I have was specifically chosen for its purpose.