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You can do it, it's pretty simple.
Pick several human subjects, expose them to bacteria, and see who survives the longest. Have the survivors reproduce with each other. Test their children to see whether their odds of survival are superior.
Pick other human subjects, do the same thing, and have them reproduce with the children of your former subjects.
Keep doing this until you finally have a family that is 100% resistant to parasites.
Congratulations, you did it!
