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Exterior frames
Pros:
>Easily changeable
>Easily fixable/replaceable
>More customization normally
>Comfortable
Cons:
>Large
>Semi heavy depends on your opinion
Interior frame
>Small
>Light
>Comfortable if the right size
Cons:
>not alot of customization
>easily breakable if plastic
>Not fixable
>Expensive to replace as you need to buy a whole new pack
Picture related my backpack I use for hiking. Comfortable and I can easily and comfortably pack 50+ pounds without any issues for 3-4 hours on a nice day without any issues.