>>2723337>Are there cooking methods to kill the prions?Nope. You could burn the food to ash and there's still a chance the prions might be intact.
You can blame thermodynamics for this. Infectious prions are naturally in a lower energy state than normal prions (which are present in all animals) and something about that state enables them to act as a catalyst to make normal prions also go into that lower energy state. And because they are in a lower energy state, they are more stable than any other proteins, and require a LOT more energy to denature.
