If you have matchsticks for shoulders and ricecakes for vertebrae, then no, it's not for you if you wanna carry any substantial weight.
If, however, you're used to carry weight without significant any significant body support, then go ahead, it's a tough piece of gear that will not fail you.
Source: I have a Rush 24, and I've taken that thing through hell and back. It's not the most comfortable at any rate, but it gets the job done without falling apart at the first mishap.