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In my experience, you want to start with gently washing and drying them. Store them in the fridge overnight, preferably a whole day. This'll firm up the skin, which tears easily. Cut them in half, scoop out the insides with a spoon. I've found two main methods of removing the seeds from the pulp. One is to dump all the pulp and seeds into a pot with an equal part water. Cook until soupy and strain. The other is to take a metal colander and metal bowl, chill them in the freezer. Throw the stuff into the colander and stir it around. Should remove most of the pulp in the bowl. The cold metal helps reduce smearing.