>>876888https://en.wikipedia.org/wiki/Heracleum_mantegazzianumThe sap of the giant hogweed plant is phototoxic; when the contacted skin is exposed to sunlight or to ultraviolet rays, it can cause phytophotodermatitis (severe skin inflammations). Initially, the skin colours red and starts itching. Blisters form as it burns within 48 hours. They form black or purplish scars that can last several years. Hospitalisation may be necessary.[9] Although many media reports on giant hogweed suggest the plant can lead to temporary or permanent blindness, existing research on the plant does not back up this claim.[15]
These reactions are caused by the presence of linear derivatives of furanocoumarin in its leaves, roots, stems, flowers, and seeds. These chemicals can get into the nucleus of the epithelial cells, forming a bond with the DNA, causing the cells to die. The brown colour is caused by the production of melanin by furocoumarins.
Authorities advise that children should be kept away from giant hogweed, that protective clothing, including eye protection, should be worn when handling or digging it, and that if skin is exposed, the affected area should be washed thoroughly with soap and water and the exposed skin protected from the sun for several days.[9]
http://www.dec.ny.gov/animals/72556.html