>>3395935If you touch the subject or something it is on and the camera with the same hand then it is really easy to do. Even without that steadiness you can completely freehand. Just use a flash and proper exposure speed, but the main thing is the program you use to do the focus stack. Like Photoshop you auto-align before combining everything. That can rotate and even resize images as needed. The further you are off from being correctly dead center the more of the edges of the image you'll need to crop off.
The biggest problem is actually occlusion. Like this one was also handheld, but there was some occlusion that really screwed it up and I didn't see fit to edit it by hand to correct it, even if it could be corrected.