>>3101130looks like about 1/30, iso 800, f5.6.
look up club/bar photography
there are some standard manual settings that people use for different effects and then just let the i-ttl on the flash do it's thing to get the exposure right.
I used to like to do 1second, f10, iso 1000 (just because they were easy to remember numbers 1s,f8,800 works about the same), with a second curtain flash to get light trails but nice in focus subjects. I would use a 28mm manual focused with the focus ring taped in place at about 1.25m. The hyperfocal point at f10 gave me about a meter and a half of DOF. So all the faces in a small group would be in focus even if they were not in the same focal plane. These settings worked great for a full frame DSLR and 35mm film. They would need to be slightly adjusted for a crop camera given the same focal length. Basically add 50% to your 1.25m mesurement (1.875m) and open the aperture by 1 stop to keep the DOF the same.
Adjust your iso to change the ambient light levels in the background till you find something pleasing and balanced with the foreground. 800-1600 works good most of the time. And then just get good at estimating how far back to stand to get your focus right and make people smile and laugh.
Works great for bars, clubs, wedding receptions. lots of keepers.
Good luck anon.