Picture is one of my dead grandfathers positive slide films from 1960's.

http://masteringfilm.com/the-practical-differences-between-film-and-digital-sensors/

I've been searching around for the past couple of months trying to find information on film and how to emulate it convincingly, a preset is not enough. Though I've been unsuccessful in finding much information, I stumbled upon this article. As stated and shown in the article, the grain structure and how it interacts with light gives film its distinct look, as well as digital. From my understanding, once the film is scanned and digitized, it would then be pixels. But even then, you can still tell film from digital.

So my question is why can't digital be manipulated to accurately resemble a high resolution digitized film scan, that a preset can't emulate? What I've come to consider is:
-film grain and structure is very organic
-dye clouds, light leaks, other imperfections
-(variability and objectively) point of focus isn't sharp or in focus at all
-dynamic range (retaining highlights when overexposing)

What are other key factors exclusive to film that may or may not be possible to emulate convincingly?

A possible solution to dynamic range is minimal HDR.

TL;DR - Physical properties exclusive to film and why a digital file can't be manipulated to accurately emulate film.
>inb4 shoot film