>>3424845645 is way larger than 35mm but half size of a 6x9 so it's a weird format. If you're shooting street, casual portraiture etc you will definitely feel the jump from 35mm to mf. For landscape, studio etc not so much, since larger formats are the norm in those fields.
That said I wouldn't skip a Fuji 645 in any way, it's a nicely build camera, outstanding iq.
