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There is something to the whole "More than 2 times a week bro" thing. Some "Nuclei" in the muscles increases. Same as with farmers who get crazy traps and forearms from carrying shit all day every day. Makes muscles overly jacked compared to onions boy, boy toys who rant about "Natty or not" geek crap.
In my opinion. Work a standard program + get drunk a few times a week and do 300 reps on the muscles you want to get overdeveloped. It just works thanks to evolution.
