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With the clarification that it will not be possible to practicably reverse the polarity of a soul (though I'm curious what the Grey Knights that we missed) we can scratch one more item off the Blank Research list. I wonder what options will remain to us?
[X] Investigate if souls polarities can be reversed to help make Blanks (They cannot)
[ ] Investigate our known Blanks, to bolster their numbers:
>If Psykers are genetic, as per Navigators, is it likely that Nulls are too? [Confirm the existence of the Pariah Gene]
>The Ancients were able to stabilize the Navigator Gene and establish growing populations. Can we do the same? [Emulate Planet 9-13 / Sisters of Silence conclaves]
>End Goal is creating a sort of reverse Navigator Houses, likely on remote planets like Xana, tasked with the raising of blanks from pure populations
All else fails, if the flesh fails us us, we shall have to just pursue the Cron's Blank Generating technology and rely on inorganic blackstone. Where flesh fails, the machine will prevail.