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Pro's and Con's, personal opinion.
Know about the Four:
PRO:
>Can develop more specific countermeasures. Stainless Adamantium and Bio Defenses against Nurgle. Emotional Suppressants against Slaanesh. Counter charms against Tzeentch. Focus on ranged fire for Khorne.
>Can develop specific virtues against the Four: Discipline over Excess. Purpose over Fatalism. Loyalty over Ambition. Honour over Rage.
>New methods to combat the Four, esp. in conjunction with our Lanterns of Charon.
>We will likely see them coming a lot easier, especially with our Brothers. Or even among our own Xenarites and proto Dark Mechanicum (this is huge). Could potentially let us slow down or blunt the impending Schism even more (This is also huge)
CON:
>Our Paranoia could be amplified
>We can't be too proactive, like trying to warn our brothers. Suck when we see our brothers susceptible to Chaos and we can do nothing.
>When our brothers question our strange ways, we won't have an adequate answer because we have to stay quiet. We'll be like Lion. May result in trust issues? (This will be worse come the Horus Heresy when we say we knew about it but did nothing)
>Unpredictable risks, such as knowledge of Chaos making one more likely to have the Eye of Chaos upon them
>Potentiality of flipping anti-chaotic defenses on its heads like so often happens (i.e. cultists realizing that if there are four virtues, then surely there are four vices. do the opposite of what Talos says!). may inadvertently make others aware of Chaos indirectly
>Biggest Con: Aesthetically it works better if we had played Magnus. Us trying to do spell stuff via the Lanterns of Charon would still work I guess.
Be Ignorant about the Four:
PRO:
>Can still focus on universally effective Null Tech and Rites which do work against Demons. We can still invoke the Machine God even without specific Chaotic Knowledge
>Gameplay wise will be simpler. We do not know the specifics, therefore we are not tempted or at risk to reveal the specifics. Our hands will remain clean
>Our Paranoia won't be amplified
>Malcador might trust us more if we show awareness that some things are best kept to secret
>Aesthetically lets us focus on the ways to fight Chaos we do best: Nulls, Pariah Tech, and Mechanicum Rites. Esp. when we discover Necrons and learn how they fight the Empyrean, not how the Imperium fights the Warp
CON:
>Lack of Specific Knowledge of the Four = Lack of Specific Defenses against the Four
>Lack of specific detection methods
>"Damn wish we had seen this coming"
>Missing out on a potentially big opportunity here
>Like a really BIG once in a lifetime opportunity