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Alright, seems like people agree to drink the vial at least. Two anons, roll 5d8. If you fail to get 6.5 or more successes, you may roll an additional 1d8 to consume the Dust and/or use your last talisman charge to reroll two dice. You may use both if you need to.
Let's see how good you are at throwing vending machines, Nicole. 1-2 = No success, 3-4 = 0.5 successes, 5-6 = 1 success, 7-8 = two successes.