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Three components for delivery, identification, and excision. A simple method of sabotaging genome editing that should– at best – be moderately functional. The complex was too inefficient for a one-time treatment, and it was certainly not processive enough to produce the clean, consistent drops in coverage you saw in your sequencing data.
This apparent inconsistency was so bothersome you chose to revisit the spectrometry reports from two nights ago. You noticed that the fusion construct was in every blood sample you analyzed, including those unaffected by immunosuppression. You found this surprising but not concerning. All refugees received the same battery of injections and vaccinations upon national entry. You doubted that the ministry of public health would raise many concerns if one of those injections included a new viral vector.
But then you paused. As an extra precaution, you withdrew a vial of your blood, presumably unchanged since you left employment at GRAIL. You suspended it in lysis buffer and processed it, watching your red blood cells break down into a cherry-red solution. The spectrometer clicked and whined before dutifully revealing the same massive peak in your own sample.
You remember blinking and reassessing. Perhaps it was a technical artifact, you had thought – lack of proper washout in an old, well-worn spectrometer. You ran a sample of solvent, followed by a sample of tap water. The solvent ran clear, indicating proper washout.
But curiously, the tap water did have a peak. Even higher than your own sample
You swabbed the window. You swabbed the water pooling outside. Everything had it. The entire city was inundated with it.
You shiver from the morning cold, and you remember this discovery as you walk through the chattering market and examine the local harvest. You remember this discovery when you watch the ministry inspectors and the Buddhist priests bless the dock-waters in advance of the new imports. South Siam is a refuge for nature, but it – like all refuges – exists through the base hypocrisy of man.
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>JOIN. Take the rest of the day off. Explore the city, and perhaps offer to take your clinical assistants to one of the religious festivals.
>READ. Your former employer sent you a message. You can read it if you want to.
>REPORT. Report your discoveries in full to the ministry of environmental purity. This may have irreversible consequences.
>CONTACT. Report your discoveries in full to GRAIL pharmaceuticals. This may have irreversible consequences.
