>>36338991A few suggestions I think are a good shakeup from the nuzlocke and monotype run.
The first one's already been mentioned, Wonder Trade, but it should be done with no dupes and one trade done per route/new area. Did USUM with this and was pretty fun.
Next run is what I call the Youngster run which is only using pokemon caught on Route 1. Kind of challenging, especially in FR/LG when you only can use Pidgey and Rattata.
Next one's the Collector run: Only using pokemon found with less than 10% encounter rate.
Final suggestion: The Jim Gai (Gym Guy) run. Each Gym victory means you must release or permanently box your team and use an entirely new one until the next gym, where you rinse and repeat. HG/SS is the best for this and it's a lot of fun.
