So, we all know those Pokémon creepypasta that are on the Internet.
http://www.youtube.com/watch?v=Zd2595c_72MAs it turns out, there is a glitch item in Red/Blue that can be used to make the game follow a little "script" of your choice, and this can persist on the game's save file.
In the video's example, the game is locked on to a fight against a GHOST shape Missingno., impossible to win without a cheating device, and the game deletes the save file and crashes afterwards.
So it's entirely possible to prepare such a file, sell the cartridge on eBay, then watch the buyer shit bricks, should he/she decide to check the saved game.