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Just beat Brock in my first ever Nuzlocke, playing FireRed. Party is:
Ippo - Lvl 11 Mankey (Caught on Rt 22)
Aznable - Lvl 10 Charmander (Starter, obviously)
Jetman - Lvl 10 Pidgey (Caught on Rt 2)
ZaBee - Lvl 10 Beedrill (Caught as Weedle in Viridian Forest)
I couldn't remember what level Brock's team was, so I spent some time grinding everyone to level 10. Nearly shit myself when I started the fight and realized his Geodude was 12 and remembered his Onix being 14 or 15.
Then Ippo 2-shot both of them with his Low Kick and it was amazing. He levelled up to 11 after the fight with Geodude. I checked his stats after the fight and realized he is Adamant nature (and so is my Charmander), so that's wonderful.
Onward to Mt. Moon! Feeling good so far, no deaths! Like that is going to last...