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Now I realize the League is far away right now, but I was thinking, what if they make it to not have Ash win? Now before you jump on me for saying that let me explain what I mean.
The League arc proceeds as usual for the most part, however Lysandre is shown to hover around for most of it as if he's preparing something. Now Ash is able to slug it out and make it to the finals, with some close calls along the way. However it is revealed that Lysandre is going to attempt a take over of Kalos, starting at the league. As such, int he middle of the match, TF performs what would basically amount to a terrorist attack and and overwhelm the league, thereby cancelling it and announcing his takeover of Kalos to create a new, better Kalos and offers anyone willing to take arms and join his side. The arc then proceeds to have TF systematically overthrow various cities around Kalos until the fall of Lumiose.
How does that sound? Too much for Pokemon? Too Autistic?