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There are two games that XY and ORAS can communicate with. ORAS is 24 and 25 and 26/27 are unknown.
There are two unused Zygarde moves. That proves that these two games are a pair and not two separate games. These moves are called Thousand Waves and Thousand Arrows.
There is likely going to be spotlight on Johto and here's the evidence. Kalos has a place called the Sea Spirit's Den which the Kanto birds roost at. Lugia is their leader and it's known as the Guardian of the Seas. Expect Mega Lugia! Take a look at the HA Johto Starter event on in the PokeBank. It lasts until November 30th. Early October to early November is the perfect time to release an XY sequel that puts some spotlight on Johto.
In Slateport City, they are discussing building a ship with the high speed rail technology from Kalos.
Not to mention all the references to Battle Frontier, Pike Queen, Scott, Champion Wallace, Match Call, and an explorer named Brandon hunting for Volcanion in Kalos.
Masuda wants to be unpredictable. He already said he won't make Pokemon Z. X2Y2 would be too predictable as well.
Think guys, the ultimate Pokemon game. These games would blow HGSS and B2W2 out of the water. Kalos and Hoenn together means two regions. Every feature from both regions in the games. Two champions, automatic Mega Milotic, expanded secret bases, ultimate character customization, every single Pokemon within two titles, and Hoenn's Battle Frontier.