>>58336206>AggronThose are easy. Assuming they're not of out-of-this-world material, you could easily defeat them with typical man-portable anti-armor weaponry, like the BGM-71 TOW.
Frankly, Metang is the bigger concern, given it can apparently take on at least a fucking TERAJOULE of energy(Metang can survive a fighter jet collision, and fighter jets can get over a trillion joules of momentum in flight,) though MAAAYBE you can get away with tank-based shaped charge munitions since that's a bit of a smaller point of contact than a figher jer.
>GhostsI dunno, just get the local priest or something. That one's much harder.
Honestly, the human world infrastructure is not build for Pokemon as they are often depicted in the anime. Charizard absolutely could bring down an entire skyscraper as a breeze. That said, we're not /totally/ defenseless.