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What if it was solely Misty that couldn't be brought back but Brock could very well return with ease, but they felt it was a little unfair to solely replace Misty, so they replaced both Misty AND Brock instead?
If the prominent theory is that they failed to retrieve the voice actors, then this has to be the case. It'll be even more evident if Misty and Brock make cameos as Gym Leaders but only Brock talks but Misty doesn't, since Ueda continues to recur in the anime.
