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His influence on Mewtwo's backstory and personality should definitely be noted.
Before the anime Mewtwo was just a wild beast living in some cave, to be thought of as nothing more than a post-game extra.
I always thought it was brilliant how Shudo took something as passable as Mewtwo being clone to expanding it to become a theme about existentialism.
Shudo's Mewtwo certainly left an impression even after the first movie. You can see this in the manga and spin-off games where aspects of the Shudo Mewtwo spill over into different incarnations of Mewtwo,
Actually, Dr. Fuji's involvement in Mewtwo's creation was arguably Shudo's original idea since before the remakes there was never any implication Fuji was even a scientist much less connected to Mewtwo's creation.
I've also read somewhere that Shudo influenced the creation of Lugia but I've also read Shudo gave himself more credit for Lugia's conception than what really happened.
