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Let's give a shout-out to both Fairies and GameFreak's incompetence ruining several mons that could have been something. Most important goes to this guy, a Pokemon that never even had a chance to shine or bloom in the metagame because some filthy slant-eye decided Dark should be weak to Fairy.
Honorary mentions include:
Zoroark because of Team Viewer, completely ruining any strategy to have with it outside of a Nasty Plot sweeper
Zangoose and Seviper for not getting Extreme Speed and/or 50 extra points to be worth a slot on the team
All the fighting types who have to deal with being yelled at, then dying
And last but not least, who can forget Beheeyem for not getting into the free 10 point stat boost club to defense.