>>55463797That's not how viruses, vaccines, or immunity works. Smallpox originally jumped from an animal species (probably cows or some other livestock but we can't be sure) to humans, and now can only live in humans. You do not randomly pick up smallpox in the wild. During the campaign of mass immunization, a significant majority of the human population was vaccinated against the disease, denying it a place to live. Once most of the human population was immune, the virus had no where left to spread to as the remaining outliers either fought off the disease naturally or died from it. And after that, the disease was eradicated. It is functionally extinct in the wild, existing only in secure laboratories for study. It's as dead as the Dodo bird. Assuming vaccination in the pokeworld progressed like it did in our world, there's no way for her to have smallpox and thus no way for her to pass it to them.
Actually, it's more likely that the opposite might happen. Once a disease has been eradicated we typically stop vaccinating against it. There's a good chance that she was never vaccinated against things like smallpox, measles, polio, etc. But the people from Hisui might have those diseases and be able to give them to her. She may be in incredible danger.